Golgi membrane protein GP73（GOLM1）

Abt-P-2017

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Descriptions

Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2 and GOLM1, is a protein which belongs to the GOLM1 / CASC4 family. GP73 is widely expressed. It is highly expressed in colon, prostate, trachea and stomach. It is expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. It is predominantly expressed by cells of the epithelial lineage. GP73 is expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GP73 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GP73 is strongly expressed in hepatocyte-derived syncitial giant cells. GP73 is constitutively expressed by biliary epithelial cells but not by hepatocytes.

Our GP73 is gene recombinant protein of mammalian cells with high purity, good immunogenicity and biological activity.

Product details：

Cat # ：	Abt-P-2017
Form:	liquid
Constituents:	Recombinant human GP73 was dissolved in 1×PBS (pH7.4).
Concentration：	1-2mg/ml
Shipment：	ice bag
Source：	A DNA sequence encoding the human GP73 (NM_016548.3) extracellular domain fused with a polyhistidine tag was expressed by HEK293 cells.
Molecular weight:	Recombinant human GP73 migrates as approximately 66-70 kDa band in SDS-PAGE under reducing conditions.
Purity：	>85%（determined by SDS-PAGE）
Storage：	4°C for frequent usage, -20°C for long-term storage. Avoid repeated freeze-thaw cycles.
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